Fructosamine is used for the diagnosis and monitoring of diabetes mellitus in cats and dogs. It is particularly useful in cats, where physiological (stress) hyperglycaemia can be marked and may lead to glucosuria and interference with the performance of blood glucose curves during therapy.

Generally fructosamine concentrations provide a reflection of blood glucose concentrations during the previous 1-3 weeks but it is important to note that other conditions may affect this analyte. Examples include hypoalbuminaemia/hypoproteinaemia, hyperlipidemia, azotemia and in cats, hyperthyroidism.

Serum fructosamine may also be useful for demonstrating prolonged hypoglycemia in animals presenting with a suspicion of an insulinoma/beta-cell tumour. Further workup to exclude other causes of hypoglycaemia and demonstrate inappropriate insulin secretion are still required to confirm a diagnosis of insulinoma.


Dog, cat


Serum (minimum 1 ml)


Plain tube

Collection protocol:

As per routine collection for serum chemistries.

Avoid haemolysis - ideally centrifuge and separate the serum before submission.